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Study Links Sleep Cannabinoid CBN to Tolerance and Withdrawal in Mice

New research in mice indicates that CBN, a cannabis-derived ingredient in sleep gummies, may produce tolerance and withdrawal symptoms.

By The Herb House Desk·October 25, 2026
Study Links Sleep Cannabinoid CBN to Tolerance and Withdrawal in Mice

New research indicates that a cannabis-derived ingredient widely used in sleep gummies may be more habit-forming than previously recognized. In tests evaluating repeated exposure, the compound produced both tolerance and withdrawal symptoms in mice.

Following the study, scientists caution that CBN may carry unexpected risks.

Source: Science Daily.

Reporting informed by public dispatches from Science Daily.